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Added April 27th, 2005

A warning has recently been issued by Health Canada regarding the possibility of a mix-up with pills, following packaging problems at the GlaxoSmithKline plant in Puerto Rico. Some of the drugs involved included Avandamet, Avandia, Coreg, Paxil, Paxil CR and Relafen. The warning that went out was to advise consumers to check medication manufactured by Glaxo to ensure that the medication in the packs or bottles is the right medication, and that no stray pills of a different type have slipped in. The warning also applied to ratio-paroxetine, a drug manufactured by Ratiopharm.
In response to the warning, Glaxo officials have stated that the chances of any mix-up are minimal, and that consumers need not feel anxious about the matter. One Glaxo official stated that the chance of patients finding the wrong medication in their bottles or packs is "extremely remote. This represents a very low risk for patients."
Inspectors from the US Food and Drugs Administration were the ones to pick up on the packaging problem at the Glaxo plant in Puerto Rico. However, Glaxo officials have stated that the issue has been resolved, but that the warning was deemed necessary simply as a safety precaution to be on the safe side.
A Glaxo spokeswoman stated: "During an inspection at the GSK plant in Puerto Rico, the FDA identified a potential for tablet mix-up and that was possibly during the cleaning and the preparation of the manufacturing line between batches. For example, it's like finding a single tablet in a difficult place to reach in the machine or finding a tablet which kind of wandered off in the packaging suite. So it's basically finding a tablet which did not belong where it should have been. Based on this observation, the FDA said there was a potential risk for tablet mix, but there was never a tablet in a prescription bottle, it never ended up in a prescription bottle, never."

Drug Mix-Up Warning... | Printable Version (Opens In New Window)